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Anxiety disorders, characterised primarily by intense and exaggerated anxiety without real threats, are frequently encountered in the general population.

Panic disorder (PD) is described as acute intense anxiety episodes occurring with or without agoraphobia. Panic attacks are often seen in emergency departments (ED).

Anxiety-related issues frequently coincide with alcohol and substance abuse, thereby complicating diagnosis. Knowledge about anxiety disorders and panic attacks is vital for clinicians in ED, as patients may feel debilitated during an anxiety attack and embarrassed afterward.


Clinical Manifestation

Anxiety presentations in ED can be categorised into:

  • Primary psychiatric illness like generalised anxiety disorder
  • Medical conditions or substance abuse mimicking anxiety symptoms (e.g., hyperthyroidism)
  • Response to either stress or stressful events, like acute stress disorder
  • Anxiety disorder occurring alongside other illnesses.
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Key Features of panic attack

PD combines physical and cognitive symptoms, with rapid onset, symptoms peaking within 10 minutes, and persisting for about an hour. A panic attack involves minimum 4 of the following signs or symptoms:

  • Palpitations or accelerated heart rate
  • Sweating
  • Shortness of breath or choking sensation
  • Chest pain or discomfort
  • Nausea or abdominal distress
  • Trembling or shaking
  • Dizziness or faintness
  • Depersonalisation or derealisation
  • Numbness or tingling
  • Chills or hot flushes
  • Fear of losing control or dying

Medical Conditions Causing Anxiety

Numerous medical conditions can cause anxiety, including cardiovascular, respiratory, metabolic, endocrine, neurological, and inflammatory disorders, as well as substance toxicity and infections.

Management

In the ED, initial assessments aim to exclude acute physical emergencies. Vital signs, blood tests, electrocardiograms, and imaging may be necessary. Screening tools can assist in diagnosing anxiety or PD, even without a psychiatrist.

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Pharmacotherapy

  • For terminating the panic attacks, rapid-onset benzodiazepines like Lorazepam, Alprazolam, or Clonazepam are considered the cornerstones.
  • Long-term treatment involves selective serotonin reuptake inhibitors (SSRIs) like Paroxetine, Fluoxetine, Sertraline, or Escitalopram. Tricyclic antidepressants (TCAs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) may also be prescribed.

Non-Pharmacological Therapy:

Reassurance of the patient during an attack helps in alleviating the symptoms.

  • Psychotherapies such as cognitive-behavioural therapy (CBT), interpersonal therapy, and mindfulness therapy are effective in the long-term.
  • Lifestyle modifications like eliminating stimulants, getting adequate sleep, and regular exercise are recommended.
  • Relaxation techniques like deep breathing exercises and guided imagery can also be beneficial.
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Role of Emergency Physicians

ED clinicians play a crucial role in recognising and managing anxiety and PD. They must provide initial treatment, and make referrals when necessary. Early intervention reduces overall costs and improves patient outcomes.

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In summary, anxiety and PD are common ED presentations. Timely recognition and treatment, including pharmacological and non-pharmacological approaches, can alleviate symptoms and improve patient outcomes.


Reference:

Raju NN, Kumar KS, Nihal G. Clinical Practice Guidelines for Assessment and Management of Anxiety and Panic Disorders in Emergency Setting. Indian Journal of Psychiatry. 2023;65(2):181.


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